What if your years of clinical trial expertise could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows - ensuring the clinical data that trains and evaluates next-generation AI systems meets the standards expected in real regulatory submissions.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the cutting edge of biomedical AI without leaving their domain behind.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10-40 hours/week
What You'll Do
Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes
Help establish the scientific standards that frontier AI systems use to understand real-world clinical evidence
Who You Are
Senior clinical scientist with deep, hands-on experience designing clinical trial protocols for regulatory submission
Expert in interpreting clinical data for major regulatory agencies - FDA, EMA, or equivalent
Strong grounding in clinical research methodology, biostatistics, or translational science
Detail-oriented and systematic - you hold data to a high standard and can articulate exactly why
Comfortable working independently in an asynchronous, remote environment
Nice to Have
Prior experience with data annotation, data quality review, or evaluation systems
Familiarity with AI tools or clinical informatics platforms
Background in drug development, medical devices, or digital health research
Experience bridging clinical and technical teams across complex research workflows
Why Join Us
Work directly on frontier AI systems that are reshaping clinical and biomedical research
Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale
Fully remote and flexible - work on your own schedule, from anywhere
Freelance autonomy with meaningful, expert-level work that matches your seniority
Collaborate with leading AI research labs and teams on genuinely novel problems
Potential for ongoing work and contract extension as projects evolve
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