Senior Principal Scientist, Global Process Development

Overview

In this Senior Principal Scientist role, you will drive strategic process development projects within Lonza’s global biologics network and lead cross-site collaborations. The position is site-based in Slough, with optional remote work up to 20% on a case-by-case basis, enabling high-precision manufacturing of biologics. You will apply deep technical expertise to solve complex challenges, influence scientific direction, and deliver innovative process solutions. This role offers high-impact leadership and the opportunity to shape technical directions across the network.

Pay / Benefits

• remote work up to 20% of time
• competitive compensation
• inclusive workplace
• multi-site collaboration
• opportunity to lead high-impact projects

Responsibilities

• Lead multidisciplinary projects to implement technology changes and ensure milestones, scope, and quality
• Head matrix teams across functions and locations to secure alignment for successful outcomes
• Provide subject matter expertise in upstream, downstream and/or bioconjugation process development and manufacturing for biologic drug substances
• Troubleshoot complex technical challenges using data analysis, multivariate approaches and root cause analysis to drive improvements
• Monitor technical performance across the network and address misalignment areas
• Present technical findings and recommendations to internal and external stakeholders to influence decisions
• Coach and mentor scientists in Process Development and contribute to broader scientific direction

Key requirements

• Extensive experience in bioprocessing with strong downstream processing and biologic drug substance development and manufacturing
• Proven track record leading complex, multidisciplinary projects and matrix teams with minimal direction
• Subject matter expertise in at least two areas of bioprocess development and manufacturing
• Experience using digital tools and advanced data analysis to understand and improve bioprocess performance
• Experience with multivariate data analysis, process optimization and structured root cause analysis
• Strong communication and stakeholder management skills for technical decisions with technical and non-technical audiences

• Strong communication
• Stakeholder management
• Mentoring and coaching
• Bioprocessing
• Downstream processing
• Biologic drug substance development

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