Regulatory Switching of Motor-Microtubule Complexes

Chaaban Lab at The Francis Crick Institute is offering a Crick PhD project focusing on the regulatory switching of a microtubule motor–scaffold complex. The student will explore how kinesin motors coordinate with regulatory partners to shape microtubule architecture during cell division.

Using biochemical reconstitution, fluorescence microscopy, cryo-EM and computational analysis, the project aims to reveal how regulatory interactions switch molecular motors between functional states and drive

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