Postdoctoral Research Associate, Cardiocvascular Research
London
The main responsibilities of this role will be to design CRISPR-mediated gene knockdown of zebrafish orthologues for novel putative Brugada genes…
The main responsibilities of this role will be to design CRISPR-mediated gene knockdown of zebrafish orthologues for novel putative Brugada genes and undertake functional analyses to assess the effect of these knockdowns on heart function. You will also be expected to implement new techniques and optimize protocols critical to the project and provide technical expertise and input for troubleshooting of experiments. It is expected that you will work with limited supervision and contribute to data analysis and interpretation.
We are looking for a person with a PhD in molecular biology, cellular biology, biochemistry or a related discipline. You should have practical expertise with gene editing methodologies and extensive direct experience of zebrafish husbandry techniques and the development of zebrafish disease models. You should also have experience in designing and executing functional assays for evaluating the effects of gene mutations, as well as excellent technical and problem-solving skills, and the ability to work effectively in a multi-disciplinary team.
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